Life goes on

This is a classic internet meme known as “It Is What It Is” (sometimes called the “Nice Guy Angel vs. Chad” meme or the “Wings of Despair” comic). It’s a darkly humorous, exaggerated commentary on dating dynamics, incel culture, and perceived female hypergamy.
Here’s the story told panel-by-panel:

A nerdy, awkward-looking guy (glasses, orange shirt) is standing alone while attractive girls ignore him and walk away or sit depressed.
Suddenly, beautiful women sprout angel wings and start flying up into the sky (symbolizing them becoming “out of his league” or ascending to date higher-status men).
The nerd reaches desperately for them, grabbing ankles, shoes, etc., trying to pull them back down or go with them.
The winged women easily lift him off the ground or drop him because he’s not strong/chad enough to hold on.
Other men (taller, more attractive “Chads”) are casually flying around with multiple winged girls holding onto them, forming human chains in the sky.
The nerd keeps trying different strategies (grabbing tighter, climbing, etc.) but always fails and falls.
In the end he’s left lying on the ground, beaten up and exhausted, staring blankly.
Final panel: “It is what it is…”

Core message (as intended by the original artist and the communities that spread it):

Average or below-average men (in looks, status, confidence) have almost no chance with attractive women.
Attractive women will literally “fly away” to date the top tier of men (“Chads”) who effortlessly collect harems.
No amount of effort, desperation, or “being nice” from the average guy changes this brutal reality.
Acceptance of defeat is the only coping mechanism left → “It is what it is.”

It’s a nihilistic, self-deprecating meme popular in incel, black-pill, and certain red-pill circles. It exaggerates reality for comedic/tragic effect but is meant to feel painfully relatable to the target audience.
So in short:
A visual representation of the belief that dating is brutally hierarchical and most men are doomed to lose the women they want to a small percentage of superior men — and there’s nothing they can do about it.2.5sFast